What are the Side Effects of HCG?

The main reason for athletes interest in human chorionic gonadotropin is that exogenous HCG has almost the same qualities as the pituitary luteinizing hormone. In men, luteinizing hormone stimulates the sex cells in the testicles and increases the production of androgen hormones (testosterone). Therefore, injectable Pregnyl is used by athletes for enhanced testosterone production. Human chorionic gonadotropin is most often used in combination with anabolic steroids (at the end or in the middle of a steroid cycle). As already mentioned, anabolic steroids on the principle of feedback inhibit the production of follicle stimulating and luteinizing hormones, resulting in reduced testosterone production. Since the body normally needs time to normalize the testosterone production process, a very difficult transition phase occurs for the athlete after discontinuation of the steroid drug, which often passes with a significant loss of strength and weight. As the steroid cycle ends, taking human chorionic gonadotropin helps to return the testicles to their original state, including their size. Temporary injections of human chorionic gonadotropin while taking anabolic steroids can prevent testicular atrophy, so many athletes take Pregnyl in the middle of a steroid cycle for 2-3 weeks. It is noticed that just at this time the athlete reaches the best progress concerning weight and force. This is explained by the fact that, on the one hand, the athlete has a high level of testosterone due to the use of HCG, and on the other — there is a high concentration of anabolic substances in the blood due to the use of steroids.

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Most athletes still take human chorionic gonadotropin at the end of the steroid cycle, so as not to “break down”, i.e. to ensure a better transition to “natural training”. Although human chorionic gonadotropin very quickly leads to a significant increase in the level of endogenous testosterone, it is unfortunately not a panacea in the fight against loss of strength and Masa at the end of the steroid cycle. As has often been observed, the athlete in this case is subject to a slow “break”. This is also stated by the American doctor, Dr. Mauro Di Pasquale in his book “Drug Use in Amateur sports” (Pasquale, 1984): “Athletes use HCG to mitigate side effects that appear when they stop taking steroids for a long time. These athletes believe that the use of Pregnyl will help them to quickly restore the production of testosterone in the testicles and bring it to normal. But this opinion is still wrong.” The fact is that although HCG stimulates the production of its own testosterone, it does not affect the arc of the “hypothalamus — pituitary – testicles” and does not lead to its recovery. After more or less prolonged use of anabolic steroids, the hypothalamus and pituitary gland are still depressed and continue to be in it when taking HCG injections, since the testosterone produced by the body due to the exogenous intake of HCG inhibits the endogenous production of luteinizing hormone. And as soon as HCG is finished, the athlete has to go through the recovery phase. Receiving HCG only postpones it.

Many athletes specializing in bodybuilding, unfortunately, still believe that human chorionic gonadotropin helps in preparation for the competition: makes their muscles harder, burns subcutaneous fat, thus better showing the lines of the figure. An excerpt from Dr. R. Kerr’s book “Practical use of anabolic steroids by athletes” (Kerri, 1982), eliminates any doubt. The instructions for use of human chorionic gonadotropin clearly state that HCG has no effect on fat burning, appetite, hunger or fat distribution. It also clearly States that human chorionic gonadotropin has proved to be a completely useless drug in the treatment of obesity and does not even accelerate the process of fat burning in a low-calorie diet.

hcg side effects

HCG Side Effects

When taking human chorionic gonadotropin, the same side effects may occur as when taking testosterone. With the increased production of testosterone, the level of estrogens also increases, which can result in gynecomastia (growth of the mammary glands). In men, there is a noticeable growth of the breast. Therefore, some athletes combine HCG with anti-estrogens. Athletes also talk about the more frequent occurrence of erection and increased sexual interest. In high doses, the drug can cause acne, as well as cumulation in the body of water and mineral salts. It is necessary to pay attention first of all to the last of the above, as excess water can lead, in turn, to edematous, baggy, watery muscles. In very young athletes, human chorionic gonadotropin, like anabolic steroids, can lead to premature completion of bone growth, resulting in small growth. One of the side effects that athletes should pay attention to is described in the book “Death in room 2” B. Toldman: “an Interesting aspect that leads to the wrong use of this drug is that men finally one day notice that they feel like they are pregnant, as they begin to suffer from fullness, vomiting, morning sickness, i.e. all the symptoms that usually delight women…” (CIT. according to Ostapenko, Klestov, 2002).

Preparations of human chorionic gonadotropin were widely used by athletes of the former GDR with its centrally controlled doping practice, which is described in detail by B. Berendonk in his book “Doping” (Berendonk, 1992).

To the use of gonadotropins and gonadotropin-releasing factors as a means of increasing the level of testosterone in the body, experts are extremely negative, since the drugs of this group in medicine are used either as diagnostic tools or for the treatment of some forms of infertility. No “normalizing” effect on the functional state of the neuroendocrine system, as can be seen from all the above, they do not have, but only prolong the “agony”, temporarily pushing, but also deepening the “poststeroid” pit. In addition, excessive stimulation of the hypothalamic-pituitary and testicular system is fraught with extremely dangerous side effects, up to the development of cancer pathology.

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